RAF Typhoon FGR4s have conducted a mission with French aircraft in a joint strike targeting an hidden munitions depot in Syria operated by the Daesh militant organization, according to the UK Ministry of Defence.
The facility, located using intelligence, was thought to be housing weapons and explosive materials, the statement said, and was situated in mountains just north of the ancient city of Palmyra in central Syria.
"Our fighter planes used laser-guided Paveway IV weapons to strike a several approach shafts down to the site... initial indications suggest the strike was effective," the ministry announced.
There was no indication of any civilian impact in the attack late on Saturday and all the aircraft returned safely, the defence officials confirmed.
The Typhoon FGR4s were backed up by a Voyager aerial refuelling aircraft.
IS - alternatively referred to as Daesh - established extremist governance over significant areas in Syria and Iraq prior to its 2019 collapse.
"This action demonstrates our UK leadership, and resolve to work closely with allied nations, to eradicate any resurgence of IS and their violent and radical beliefs in the region," UK Defence Secretary the minister stated.
UK warplanes have performed patrols over Syrian airspace to "prevent any attempted resurgence" of Islamic State following its defeat at the climactic battle in Baghuz in the year 2019, the authorities noted.
"I must thank every member of our armed forces participating in this mission for their skill and their bravery," Healey added. "They were among numerous UK service members deployed over the holidays. This action, to eliminate dangerous terrorists who threaten our way of life, highlights how UK forces are prepared to act, all year round, keeping Britain secure at home and powerful internationally."
In December, the United States armed forces carried out what it described as a "massive strike" against IS targets in Syria, after an assault claimed the lives of two American soldiers and a local interpreter in Palmyra.
The United Nations says IS still boasts an estimated 5,000 to 7,000 fighters in Syria and Iraq.